This article was inspired by a Subscriber’s recent comment in the article entitled, REPOST: Ivermectin May Defeat Cancer and Other Common Chronic Diseases of Aging, where he shared his positive and most surprising “side effect:”
Ivermectin must be some kind of magic bullet that effectively treats a multitude of health issues because the deep state went all out to surpress it during the great ConVid scam after it had been used safely & effectively for years all over the world
I know they've been doing everything in Europe to ban Supplements & Vitamins while bastards like Rockefeller had his own Homeopath & only took Natural Herbal Remedies which enabled the old shit to live up to his 90's whilst he foisted his toxic Petrochemical Allopathic junk on the masses.
Unfortunately ppl dont appreciate the magnitude of the situation - these evil monsters are going to take everything, especially if it's useful in preventing & treating disease or has any beneficial effect on health & fitness.
Just look at the Lockdowns & the evil damage that did to little children who couldn't learn to speak properly because ppls mouths were covered & they couldn't see them to learn how to make sounds properly onto top of all the other developmental setbacks they endured.
Quite frankly we are under Full Spectrum Dominance Fifth Generational Warfare but the bulk of society is walking around like it's just another ordinary day.
We need to get organized in all spheres to ensure we survive & that means talking back control of your food, water, medicines, etc. They day is fast approaching when we will have to smuggle in black market style or create our own facilities to produce medicines for ourselves or find an effective botanical replacement fast. The situation is not going to improve, it will get worse.
I concur. People in my circle are either scared to speak of it or have their heads up their asses as they peruse tmz for kardashian's latest shitshow, fascistbook for funny cat videos, or espn for the latest sportsball scores. Hundreds of successful distractions are ongoing for the normies while the serial killers continue their "work." But forums like these help us realize that we are far from being alone.
Wake up indeed, and stock up as well. The killers are on the loose and have unlimited resources. God bless and help us all.
Yes, the shadows on Plato's cave distracting the masses that they're in prison - dont give the ppl History, Art, Civilisation, real true Science (not junk Science we are insulted with today - like men can have babies) the beauty of the Natural World, inspirational stories of brave selfless deeds etc - no, feed them crap to dull their minds, make them stupid & lazy, fill their days with meaningless dross & porn, teach them greed, cowardice & likes - Never let them rise to become brave true souls.
Well good for them if they fall for that rubbish - I refuse to submit to the Idiot Protocol - I will speak out when others cringe - I will refuse when other aquiese - I will be a thorn in their side - I will disrupt they're evil NWO Agenda.
I will not go quietly to my doom because when I meet my maker - Lord God Jesus Christ, he will know me for kicking up a shitstorm against his satanic enemies & that alone makes it all worth it - tho I do hope we win in the end : )
I would say most people enjoy having their heads up their asses and ignore it. I try to enlighten people daily, but its obvious some just don’t think its necessary to prepare or bother their little heads about it. Thank God for these forums….its what gets me through all this.
In NZ we have now got in place a new Therapeutics law which passed recently. This new law sets up a board to discuss and decide what natural remedies NZders may have access to. The list of items that are being considered is extremely extensive and even includes things like ginger, cinnamon and other herbs that may even be used daily in cooking. Goodness knows how long the appointed government sycophants will talk and debate in their great wisdom! There were many, many submissions against this law but it made no difference at all.
When I ordered some product from this website, it was seized at our border; this is what we are up against. Ivermectin is extremely difficult to come by, as is Hydroxychloroquine, most Doctors refuse to prescribe such items and certainly not for covid! We are considered too stupid to take meaningful steps to care for our own health. Our opinions and requests are ignored.
My husband has had serious cancer a number of times (including throat cancer) and has now got some very nasty lesions on his face. I would like to have a cream to apply made from those products referenced here, and also the appropriate tablets but it is no go. It is cruel imho.
Oz & NZ really got hammered by all this, it's incredible.
I feel for your husband, he should be able to make decisions about his health & what treatments he wants to have - banning Cinnamon & Ginger!!
You can grow your own Ginger by planting a piece from the shops, you can make a DIY version of Hydroxy by taking real herbal Tonic Water (Quinine) with high strength Zinc tablets.
Black Seed Oil, Ground Golden Flaxseed (buy Organic & blitz in a
Coffee grinder mins b4 you consume them to get the good oils fresh) preferably in a high nutrient smoothie with stuff like Spirulina, Chlorella, Young Barley Grass, Curcumin or Tumeric powder - eat piles of raw garlic - Cancer Hates it!
Try & get some Chlorine Dioxide - look it up at Universal Antidote - it's made of 2 pts & if pushed you could just buy the raw salts & make it yourself - it's a great Anti Cancer treatment & the Deep States hates it because it can cure almost anything - you can use it on pets & animals & it will heal them too.
You'll have to adapt to the challenges, find other substitutes - Fasting puts the body into Autophagy which is when it can do a deep clean out of cells & flush dead junk out.
Hydrogen Water & Hydrogen Gas therapy are great for fighting Cancer - Dr Mercola dies High Strength Hyroden tabs if you can get some.
I'd drop all meats & only eat organic raw veg - it's the Diet you get put on at all the most expensive clinics in Switzerland where all the rich go because it's so Healing for the body.
Absolutely no Sugar - it feeds Cancer, stop using perfumed Washing Detergent on your washing - highly toxic
Theres loads more - I could go on & on but you'll need to research for yourself. Happy to send more info if you leave a comment
Wishing you both all the best - fight like hell, don't get down - you still have each other
on YouTube - poor ppl couldn't afford Dr's so they healed themselves & this man is still making those old time natural remedies so you might find some useful & inventive remedies - get into Folk Healing, grow a Medicine Garden full of Herbs
Yes, it is disheartening to say the least when we hear people so out of touch. I hear people complaining that 5G hasn't improved their internet/WiFi reception and others singing the praises of Alexa. They just don't get it.
I think they need to saturate the area in cell towers to get the speed up which is why they were throwing them up during the Lockdowns - they seem to have jabbed some ppl with Graphene Based Hydrogel & Quantum Nano Tech that reacts to 5G to enable the Graphene & Nano Tech to grow into some sort of mini machine or system that will have some sort of effect other than death on the jabbed victim - possibly some kind of mind control.
It's inexplicable why some ppl get all this easily & others not at all - I can't offer an explanation because some highly educated ppl dont see it but moderately educated ppl do - so it's not an intelligent issue - it must be Spiritual
Spirituality gives discernment - not necessarily Religion - Spirituality itself
I am right here with you. We need to organize and fast. State by state, by region and nationally to protect and stop their assault on us. What state are you in? I am in Ohio.
Power to you - wish I could get it together with like minds to secure future safety & survival but I'm across the Pond & very much alone - just my cat & he's not bothered !!!
I have to laugh at the cat! Thank you, I wish we could join forces. We will do it from a far. God bless you and keep you safe! I feel alone a lot. Too many people with their heads buried.
Seems like these anti-parasitic meds are the key. Interesting that parasites are the base of everything harmful to humanity. Requires some big picture thinking.
I’ve had my 84 year old relative on this for 2 1/2 years because he was being treated for stage 4 stomach cancer for years. It had metastasized to his liver after his oncologist made him get the DEATHVAX. His latest PET scan showed zero tumors anywhere. !!!!
One positive outcome from the covid shitshow is that some have been forced to take control of their own health and question medical dogma. Hidden in plain sight were vitamin D, ivermectin and fenbendazole which we now know help prevent (vitD) and eradicate cancer (IVM, FBZ).
What would a protocol look like for managing or eliminating things like inflammation, which is the source for all sorts of bodily havoc? Is it taken daily for the rest of your life? Once a week? Etc?
Most people could benefit from 8000-10,000 IU vitamin D3 per day to help optimize their immune system. A properly functioning immune system, which ‘runs’ on vitamin D, will not attack healthy tissue...which is what autoimmune disease is. Currently the ideal serum level of vitD is 80-100 ng/ml using the 25(OH)D3 blood test, the dose above should get you into that range.
This amount is much higher than the US RDA which is 600 IU per day. This amount is barely enough to keep bones from crumbling! Keeping the population chronically vitD deficient by misinformation and villification of the sun creates customers for life for big pharma treatments to band-aid over the symptoms. Virtually all autoimmune disease can be prevented with adequate vitD and many autoimmune diseases can be cured with vitD. Fun fact: any new ‘miracle’ biologic whose name ends in ‘ib’ or ‘ab’ is an engineered version of vitamin D. For example, all the psoriasis biologics manipulate the interleukins, mostly IL-6 and IL-17. VitD does the same thing...without any side effects like the biologics. Why do the biologics have side effects while vitD doesn’t? Remember the commercial whose tag line was “It’s not nice to fool with Mother Nature...”
Same thing with artemisia annua---chemists had extracted artemisinin, but found, oddly, that it didn't have the same beneficial effect as the whole herb. (PubMed article on medicinal benefit of artemisia). A personal note: suffering from a many-day bad sore throat, I made artemisia annua tea, Monday--found it quite pleasant in an herby-way. Made tea from artem. absinthium yesterday--nasty stuff. Perhaps I used too much.
Strive to live an anti-inflammatory lifestyle. This would include eating a WFPB diet, exercise, being outside in nature (did you know that walking in a forest confers all kinds of health benefits?), intermittent fasting, observing your thoughts and reducing/stopping negative thinking. Consider buying an infrared sauna (Sunlighten is brand we have)... check out Dr. Zach Bush, Dr. Stephanie Sennef. Once you comprehend you are your own doctor, it changes everything for the better. When you are emancipated from western medicine ideology, you will experience true liberation! My best to you! Have no fear!!
I take a 12mg Ivermectin tablet once-a-week, along with a 50mg Zinc tablet, along with my other OTC vitamins. I've been doing this as a prophylactic for several months now.
Recently, I've developed some pain and swelling in a pinky finger on my right hand. I had it checked out and X-ray'd by my Ortho Dr. and he indicated that is mildly arthritic.
Question; how often is Ivermectin recommended to be taken? I guessed at once a week as I read somewhere that Ivermectin stays in the body for approximately 6 days?
I have bad arthritis in my spine and deal with a lot of back pain. I took 12 mg of ivermectin for about ten days and saw zero improvement in my back pain. Maybe I needed a higher dose for longer. If anyone has any suggestions, I’d like to hear them.
It could really be that almost everyone has parasites. They are super inflammatory, hard to detect and our medical system will not acknowledge they exist in 1 st world countries. It’s almost as if they don’t want to look for them so you will develop cancer or arthritis. Much more profitable.
100%.... a parasite cleanse including wormwood and anti-parasitics helps many conditions but it needs to be done regularly not just once..... we de-worm our animals but we have stop doing this to ourselves.... we had the wisdom and we were able to take care of ourselves without big pharma or mandates....we have forgotten because they made sure we would forget
It is derived from nature-a fungus in soil from Japan. Firsthand account-a friend of mine 73 yeats old with arthritus knee ad burcitous in elbow, 3 days of Iver all swelling dissapeared and regained all knee movement no pain! Swelling dissapeared.
Oct 7, 2023·edited Oct 7, 2023Liked by 2nd Smartest Guy in the World
Hi! Smartest Guy bar one!
This is a personal enquiry, although I don't know if your credentials allow you to give an 'expert' opinion.
I'm nearly 79, around 155 lbs, fit, active and generally healthy. I can still do 50 press-ups and 200 leg lifts, although periodically these days.
My problem is that because I played local league soccer until 60 every Saturday, Sunday and midweek training during the soccer season, I now have worn joints.
I've had a worsening left hip issue for over 20 years and a right knee problem that causes me to avoid taking too much pressure or weight on that knee. I've been on an NHS hip replacement list for around 15 years but keep saying "it'll do me until next year". So I postpone the op for another year. The Consultant who i visit annually, understands my reasoning that I could be the 1 in 1000 the op goes badly and end up with less mobility than I currently have.
I've been an advocate of IVERMECTIN over the DEATH SHOT since day one (December 2019) and you seem to keep finding many other ailments IVM can assist with. Obviously IVM is primarily an anti-viral medicine, but it seems to be assisting more ailments than seem realistic.
I bought IVM back in 2021 but, apart from sampling one (to see if it killed me) I've not had occasion to test the pills for Covid/Flu or the common cold (possibly all derivatives of each other???).
Our IVM stash came from India so we're not positive it's 'PUKKA' (Boom Boom).
With your latest suggestions it seems IVM might ease rheumatism/arthritis (hip wear) which is what hip replacements are suppose to alleviate.
Have you any knowledge of IVM for worn joint issues?
Mick, I am not a medical doctor, and this Substack does not provide medical advice. You will have to extrapolate and perhaps ask your fellow subscribers their opinions on the matter.
I do like that 'extrapolate'. It is rewarding to read between your words, just as it was to 'listen between words' two years ago, as John Campbell turned around (but delicately) on the injection issue.
I’m 64 years old and have had juvenile rheumatoid arthritis most likely since I was an infant or toddler. I was “diagnosed” by my pediatrician at age 5 with “arthritis” and then “officially diagnosed” with JRA in ALL joints at age 12. I was also diagnosed at age 37 with Psoriatic Arthritis. So by age 5 I’d lost my ability to cross my legs, sit Indian style, sit on the back of my legs (sorry, not sure how to describe that). Also since then I’ve had a heck of a time getting up and down from the floor and walk like a very old woman (yes, since kindergarten). Also in early elementary school, I lost the ability to make a fist and to bend my wrists in any direction. And of course it’s gotten much worse since then. I’ve had 5 total joint replacements beginning at age 27 and many fusions (surgical and natural) including my lower back. I’ve been told I need surgical intervention on most my remaining joints but I figured they were causing at least as many problems as they solved (I.e., muscle, tendon, and gait issues). I’ve tried many medications but have mainly stuck with hydroxycloriquine and methotrexate.
So that’s a basic overview and I’ve left a lot out but my question is this - would/could ivermectin even help me at this point? I still have lots of inflammation in my joints but I feel it’s mostly due to damage from the JRA (I’m bone on bone in the majority of my remaining joints). It’s nearly impossible to get any of my doctors to test my Vit D levels but the 2 times they did, it was horribly low and high dose Vitamin D was temporarily prescribed. All they really want to do is prescribe biologics but I’ve mostly refused. Also if I start taking Ivermectin, do I immediately stop the other meds? I have so many questions yet no one to ask. Any suggestions for me there?
Thank you for replying. We do have one functional doc here but they don’t deal with anything resembling my issues. FLCCC shows one functional doc 90 miles away and I just might call them this week. Thank you again.
IVERMECTIN - Certainly a safer bet than Pfizer's depopulating POISON they pretend is VACCINE!
Could it really be that the disgusting lack of (Vax) quality and efficacy is deliberate? It seems likely.
Not even the most incompetently run organisation could produce 100% useless, dangerous and ineffective crap - unless it was DELIBERATE!
And all this DEADLY garbage being injected with NO LIABILITY for the murdering manufacturers!
Hasn't every man in the street realised what's going on yet? It's nothing to do with the man-enhanced bat virus - but simply about GUARANTEED PROFIT with no regard for the deadly consequences and, of course, population reduction! Courtesy of the WEF's (New World Order).
We know your game and we're coming for you! Be very afraid!
A friend of my mine and my husband has CLL (like me) and his wife has had rheumatoid arthritis since high school (we are all in our 60's). The difference between that guy and me is that he has done ZERO research into what kind of CLL he has, and trusts his oncologist to take care of him (ha, ha) As soon as I know that the IVM and Fenben I'm taking is working for me-which I have no doubt it is-I will get them both to take at least IVM. I've already gotten them on vitamin D, which none of their doctors has ever even mentioned to them, just like the doctor that diagnosed me didn't. When I asked her what I should do for my CLL, her reply was "we'll just watch and wait". Unconscionable!
My friend had a chronic knee problem for most of his life. He lives in Vancouver BC, not a friendly environment for arthritus. He has a second home in Scottsdale Arizonia, where he comes for the desert sun. In may his knee started to cause so much pain he could hardley walk. Went to many chiropractures who used the latest GIZMO technologies ultrasound etc, who said thats all we can do. He ended up a heavy user of Tylonol to mask the pain. He is well aware of the Agenda 2030 and all the evil of kill hot. Being a Canook , he was forced to get jabbed for travel. He knew about properties of Iver for Flu/viral infection (refuse to use word COVID((fear porn)). His elbow started a fluid builup
in elbow (looked like a tennis ball size inflammation., I read about Iver success as anti inflammatory
properties and I suggested he try it, as he had nothing to lose except pain. !2 mcg in morning, 8 ounces of water. wait 1 hour before eating and 3 days later. NO PAIN, 100% knee and elbow normal. He doesnt take Iver, as only when needed. He was truly amazed, as the Phar mafia pain management industry isn't to thrilled about these studies! Being a Canadian he spent about 7 grand for tests etc at the Mayo clinic!
I’m 79 and ~ 200 lbs. Recently got something flu like that wouldn’t go away. Took 12 mg ivermectin daily without affecting it. The day after I took 24 mg it almost disappeared. Recommended aggressive dose for me is about 38 mg.
So kind of you to help Liz and thank you for setting such a good example for other caring people to follow. The info you gave can be very hard to find but is the info that so many seek in desperation. Sadly, very few are willing to answer. We all need to help each other from that place of compassion that lives in our hearts. It is starting to appear that this may be the only real way we have to get out of this nightmare. Thank God for people like yourself🙏 You have inspired me for sure!
After pondering all the data on these videos about parasites; it now make more sense as to why CDC, WHO, et al were vehemently against Ivermectin and the seldom mentioned Fenbendazole.
The self protection mechanism of a parasite is clever.
EDTA to rid heavy metals is one more reason to detox.
May God Almighty have mercy on us all.
We are in a fight for our eternity, against all the lies and damn lies...!
Is the Ivermectin taken daily of less often? Is there a standard dose or is it by weight? I've been taking a 12 mg capsule 2X a week, but I haven't noticed much difference in my knee pain. Maybe take more often or a higher dose? Who might have some ideas? Thank you!
Diabetes, Non-Alcoholic Fatty Liver disease, and other Metabolic disorders: "Remarkably, ivermectin displays antidiabetic activities by reducing blood glucose and cholesterol levels, and also by improving insulin sensitivity in an FXR-dependent manner. Our observations therefore indicate that ivermectin may represent a unique safe approach for designing novel FXR ligands for therapeutic purposes."
"We used a mouse asthma model, in which allergic airway inflammation and airway remodelling were induced by ovalbumin (OVA) sensitisation and challenge. Ivermectin or PBS treatment was administered 1 h before OVA challenge. Ivermectin at 2 mg/kg significantly diminished recruitment of immune cells, production of cytokines in the bronchoalveolar lavage fluids and secretion of OVA-specific IgE and IgG1 in the serum. Histological studies indicated that ivermectin suppressed mucus hypersecretion by goblet cells in the airway."
Recently, a specific inhibitor of nuclear import has been identified that inhibits importin α/β-dependent import with no effects on a range of other nuclear transport pathways involving members of the importin protein family. In this study we evaluated the physiological activity of this importin α/β-inhibitor (Ivermectin) in the hypoxia response pathway. Treatment with Ivermectin decreases binding activity of HIF-1α to the importin α/β-heterodimer. Moreover, HIF-1α nuclear localisation, nuclear HIF-1α protein levels, HIF-target gene expression, as well as HIF-transcriptional activity are reduced upon Ivermectin treatment. For the first time, we demonstrate the effect of specific importin α/β-inhibition on the hypoxic response on the molecular level.
"There are several theories that explain how anosmia occurs in COVID-19 patients. It is claimed that coronaviruses invade the olfactory pathway through the first order neuron of the central nervous system which presents in the olfactory mucosa. This olfactory mucosa is located in the roof of the nasal cavity and is formed of a specialized neuro-epithelium. The virus reaches the second order neuron by crossing the cribriform plate, and then reaches the olfactory bulb. One potential mechanism for the anosmia brought on by COVID-19 is olfactory epithelium(OE)inflammation. The virus’s attachment to these cells results in cytokine production, which encourages OE inflammation. In one study, IL-6 levels and olfactory abnormalities in COVID-19 patients were compared. Significant relationships between the lowered levels of IL-6 and the length of time needed to recover from anosmia brought on by COVID-19 have been reported. Ivermectin interferes with STAT-3 function and reduces IL-6 production via inhibiting Akt/mTOR signalling and promoting PAK1’s ubiquitin-mediated degradation.The reduction of cytokine production by lipopolysaccharide-exposed macrophages, blocking of NF-kappa B activation and the stress-activated MAP kinases JNK and p38, and inhibition of toll-like receptor 4 (TLR4) signalling were proposed as the mechanism for ivermectin’s anti-inflammatory activity. The results of this study showed a significant reduction in the duration of recovery of patients with persistent post-COVID-19 anosmia. Also, no side effects were reported. In this study patients with persistent post-COVID-19 anosmia treated by local ivermectin in the form of nanosuspension mucoadhesive nasal spray showed statistically significant improvement in the first week of treatment in comparison to the placebo group. The effect of ivermectin nanosuspension mucoadhesive nasal spray in the treatment of post COVID-19 persistent anosmia may be attributed to the direct virucidal effect of ivermectin on persistent viral particles or virions on the nasal mucosa and olfactory bulb, although further molecular research to highlight the mechanism of local ivermectin in recovery of post-COVID-19 anosmia is required."
"Some antiepileptic and anxiolytic attributes have been reported for IVM in numerous animal models and in clinical trials. A possible pharmacological mechanism of IVM is the contribution of the gamma-aminobutyric acid type-A (GABAA) receptor to its effect and thus it has been suggested that avermectin B1a acts on a modulatory binding site of benzodiazepine receptor and could stimulate it. In other words, IVM acts as a positive allosteric modulator of the GABAA receptor. It has been well established that GABAergic system, and specially GABAA receptors have been considered the main inhibitory neurotransmitter in the central nervous system (CNS), involved in modulating seizure threshold."
"IVM may be a good therapeutic tool to inhibit the cytokine storm and prevent ARDS in the following pathways. IVM blocks the IMPα/β1-dependent nuclear import of viral proteins (NS12-RdRp) as mentioned prior. IVM also inhibits the activity of STAT3, subsequently reducing inflammatory IL-6 cytokine production. Besides that, IVM promotes the ubiquitination-mediated degradation of p21 activated kinase 1 (PAK1), a key protein that binds to STAT3 for IL-6 gene transcription, disrupting IL-6 production. The reduction of STAT3 levels by IVM could also bring down HA levels, preventing ARDS in Covid-19 patients. IVM also binds to the viral S protein, thereby prohibiting the attachment of S protein to the host ACE2 receptors for viral entry and reducing the viral load."
Multiple Sclerosis:
"Multiple sclerosis (MS), a T-cell-mediated autoimmune disease that affects the central nervous system (CNS), is characterized by white matter demyelination, axon destruction, and oligodendrocyte degeneration. Here, we conducted in vitro experiments and found that ivermectin inhibited the proliferation of total T cells (CD3+) and their subsets (CD4+ and CD8+ T cells) as well as T cells secreting the pro-inflammatory cytokines IFN-γ and IL-17A; IVM also increased IL-2 production and IL-2Rα (CD25) expression, which was accompanied by an increase in the frequency of CD4+CD25+Foxp3+ regulatory T cells. IVM administration reduced the clinical symptoms of EAE in mice by preventing the infiltration of inflammatory cells into the CNS. Additional mechanisms show IVM promoted Treg cells while inhibiting pro-inflammatory Th1 and Th17 cells and their IFN-γ and IL-17 secretion. IVM also upregulated IL-2 production from MOG35–55-stimulated peripheral lymphocytes. Finally, IVM decreased IFN-γ and IL-17A production and increased IL-2 level, CD25 expression, and STAT5 phosphorylation in the CNS. These results reveal a previously unknown etiopathophysiological mechanism by which IVM attenuates the pathogenesis of EAE, indicating that it may be a promising option for T-cell-mediated autoimmune diseases such as MS. IVM has been shown to stabilize the open state of P2X4 receptor channels, which bind to extracellular adenosine triphosphate and are involved in neurodegenerative disease."
"Topical IVM improved allergic skin inflammation by reducing the priming and activation of allergen-specific T cells, as well as the production of inflammatory cytokines. While IVM had no major impact on the functions of dendritic cells in vivo and in vitro, IVM impaired T-cell activation, proliferation, and cytokine production following polyclonal and antigen-specific stimulation."
IVM Enhances Anticancer Efficacy of Chemotherapeutic Drugs & Reverses Drug Resistance in Cancer Cells Through EGFR/ERK/Akt/NF-κB Pathway:
"Mechanistically, ivermectin reversed the resistance mainly by reducing the expression of P-glycoprotein (P-gp) via inhibiting the epidermal growth factor receptor (EGFR), not by directly inhibiting P-gp activity. Ivermectin bound with the extracellular domain of EGFR, which inhibited the activation of EGFR and its downstream signaling cascade ERK/Akt/NF-κB. The inhibition of the transcriptional factor NF-κB led to the reduced P-gp transcription. These findings demonstrated that IVM significantly enhanced the anti-cancer efficacy of chemotherapeutic drugs to tumor cells, especially in the drug-resistant cells."
"We originally identified the small molecule ivermectin as an inhibitor of recognition of HIV-1 integrase (IN) by the importin (IMP) α/β1 heterodimer responsible for IN nuclear import, subsequently establishing ivermectin's ability to inhibit integrase nuclear import and HIV-1 replication. Although other actions of ivermectin have reported, including those targeting DENV NS3 helicase, ivermectin has been clearly shown to inhibit nuclear import of host and viral proteins, including simian virus SV40 large tumour antigen."
In the good old days (Pre-Covid), we could ask our local MD, but things have changed dramatically. The Doctor cannot see humans. He might now be a programmed robot. He forgot his Hippocratic Oath to 'Do No Harm'. He forgot to tell his patients about the many adverse reactions and DEATHS that occur following the useless but deadly Covid injections he refers to as VACCINES! He forgot to tell, his patients that the injection makers bare no responsibility for anything/everything that goes wrong with your health following the injection. He does not confirm Vax recipients are giving 'informed consent'. He's not responded to any of the information I've sent his practice about the proven 'vax' dangers, since the Covid & Vax farce began.
My hip would be a topic he would be reluctant to discuss with me, so I'll have to look elsewhere for health advice. Thanks for your input with your findings to date and if you find any other information relating to IVM and 'arthritis', please let us all know - we understand it's not your medical advice but simply passing on good information.
Ivermectin must be some kind of magic bullet that effectively treats a multitude of health issues because the deep state went all out to surpress it during the great ConVid scam after it had been used safely & effectively for years all over the world
Bastards
I worry that these sons of bitches will pay off or burn down facilities that produce medications that threaten their agenda.
Very good point
I know they've been doing everything in Europe to ban Supplements & Vitamins while bastards like Rockefeller had his own Homeopath & only took Natural Herbal Remedies which enabled the old shit to live up to his 90's whilst he foisted his toxic Petrochemical Allopathic junk on the masses.
Unfortunately ppl dont appreciate the magnitude of the situation - these evil monsters are going to take everything, especially if it's useful in preventing & treating disease or has any beneficial effect on health & fitness.
Just look at the Lockdowns & the evil damage that did to little children who couldn't learn to speak properly because ppls mouths were covered & they couldn't see them to learn how to make sounds properly onto top of all the other developmental setbacks they endured.
Quite frankly we are under Full Spectrum Dominance Fifth Generational Warfare but the bulk of society is walking around like it's just another ordinary day.
We need to get organized in all spheres to ensure we survive & that means talking back control of your food, water, medicines, etc. They day is fast approaching when we will have to smuggle in black market style or create our own facilities to produce medicines for ourselves or find an effective botanical replacement fast. The situation is not going to improve, it will get worse.
Wake Up
We Are At War
I concur. People in my circle are either scared to speak of it or have their heads up their asses as they peruse tmz for kardashian's latest shitshow, fascistbook for funny cat videos, or espn for the latest sportsball scores. Hundreds of successful distractions are ongoing for the normies while the serial killers continue their "work." But forums like these help us realize that we are far from being alone.
Wake up indeed, and stock up as well. The killers are on the loose and have unlimited resources. God bless and help us all.
Yes, the shadows on Plato's cave distracting the masses that they're in prison - dont give the ppl History, Art, Civilisation, real true Science (not junk Science we are insulted with today - like men can have babies) the beauty of the Natural World, inspirational stories of brave selfless deeds etc - no, feed them crap to dull their minds, make them stupid & lazy, fill their days with meaningless dross & porn, teach them greed, cowardice & likes - Never let them rise to become brave true souls.
Well good for them if they fall for that rubbish - I refuse to submit to the Idiot Protocol - I will speak out when others cringe - I will refuse when other aquiese - I will be a thorn in their side - I will disrupt they're evil NWO Agenda.
I will not go quietly to my doom because when I meet my maker - Lord God Jesus Christ, he will know me for kicking up a shitstorm against his satanic enemies & that alone makes it all worth it - tho I do hope we win in the end : )
Well, indeed, he promised that if you deny him on earth, he will deny you in heaven. And I infer that the reverse is true.
I would say most people enjoy having their heads up their asses and ignore it. I try to enlighten people daily, but its obvious some just don’t think its necessary to prepare or bother their little heads about it. Thank God for these forums….its what gets me through all this.
'Strength doesn't come from physical capacity - it comes from indomitable will'
Ghandi
In NZ we have now got in place a new Therapeutics law which passed recently. This new law sets up a board to discuss and decide what natural remedies NZders may have access to. The list of items that are being considered is extremely extensive and even includes things like ginger, cinnamon and other herbs that may even be used daily in cooking. Goodness knows how long the appointed government sycophants will talk and debate in their great wisdom! There were many, many submissions against this law but it made no difference at all.
When I ordered some product from this website, it was seized at our border; this is what we are up against. Ivermectin is extremely difficult to come by, as is Hydroxychloroquine, most Doctors refuse to prescribe such items and certainly not for covid! We are considered too stupid to take meaningful steps to care for our own health. Our opinions and requests are ignored.
My husband has had serious cancer a number of times (including throat cancer) and has now got some very nasty lesions on his face. I would like to have a cream to apply made from those products referenced here, and also the appropriate tablets but it is no go. It is cruel imho.
How utterly awful
Oz & NZ really got hammered by all this, it's incredible.
I feel for your husband, he should be able to make decisions about his health & what treatments he wants to have - banning Cinnamon & Ginger!!
You can grow your own Ginger by planting a piece from the shops, you can make a DIY version of Hydroxy by taking real herbal Tonic Water (Quinine) with high strength Zinc tablets.
Black Seed Oil, Ground Golden Flaxseed (buy Organic & blitz in a
Coffee grinder mins b4 you consume them to get the good oils fresh) preferably in a high nutrient smoothie with stuff like Spirulina, Chlorella, Young Barley Grass, Curcumin or Tumeric powder - eat piles of raw garlic - Cancer Hates it!
Try & get some Chlorine Dioxide - look it up at Universal Antidote - it's made of 2 pts & if pushed you could just buy the raw salts & make it yourself - it's a great Anti Cancer treatment & the Deep States hates it because it can cure almost anything - you can use it on pets & animals & it will heal them too.
You'll have to adapt to the challenges, find other substitutes - Fasting puts the body into Autophagy which is when it can do a deep clean out of cells & flush dead junk out.
Hydrogen Water & Hydrogen Gas therapy are great for fighting Cancer - Dr Mercola dies High Strength Hyroden tabs if you can get some.
I'd drop all meats & only eat organic raw veg - it's the Diet you get put on at all the most expensive clinics in Switzerland where all the rich go because it's so Healing for the body.
Absolutely no Sugar - it feeds Cancer, stop using perfumed Washing Detergent on your washing - highly toxic
Theres loads more - I could go on & on but you'll need to research for yourself. Happy to send more info if you leave a comment
Wishing you both all the best - fight like hell, don't get down - you still have each other
Check out
Ole Time Living channel
on YouTube - poor ppl couldn't afford Dr's so they healed themselves & this man is still making those old time natural remedies so you might find some useful & inventive remedies - get into Folk Healing, grow a Medicine Garden full of Herbs
Yes, it is disheartening to say the least when we hear people so out of touch. I hear people complaining that 5G hasn't improved their internet/WiFi reception and others singing the praises of Alexa. They just don't get it.
It's going to be 6G soon!
I think they need to saturate the area in cell towers to get the speed up which is why they were throwing them up during the Lockdowns - they seem to have jabbed some ppl with Graphene Based Hydrogel & Quantum Nano Tech that reacts to 5G to enable the Graphene & Nano Tech to grow into some sort of mini machine or system that will have some sort of effect other than death on the jabbed victim - possibly some kind of mind control.
It's inexplicable why some ppl get all this easily & others not at all - I can't offer an explanation because some highly educated ppl dont see it but moderately educated ppl do - so it's not an intelligent issue - it must be Spiritual
Spirituality gives discernment - not necessarily Religion - Spirituality itself
Did anyone else see the massive die off of birds during the Oct. 4th drill?
Kim D what did you see?
I am right here with you. We need to organize and fast. State by state, by region and nationally to protect and stop their assault on us. What state are you in? I am in Ohio.
Power to you - wish I could get it together with like minds to secure future safety & survival but I'm across the Pond & very much alone - just my cat & he's not bothered !!!
Bonne Chance mon amiee!!
I have to laugh at the cat! Thank you, I wish we could join forces. We will do it from a far. God bless you and keep you safe! I feel alone a lot. Too many people with their heads buried.
haha - yes, he's a very fine Cat but he's got it soooooo good he couldn't care less - I'm mad enough for the both of us!!!
Thank you for the kind words - warmly appreciated by myself & said spoilt cat,
You know where I am
Keep the faith & give them hell
That's my plan : )
Seems like these anti-parasitic meds are the key. Interesting that parasites are the base of everything harmful to humanity. Requires some big picture thinking.
I’ve had my 84 year old relative on this for 2 1/2 years because he was being treated for stage 4 stomach cancer for years. It had metastasized to his liver after his oncologist made him get the DEATHVAX. His latest PET scan showed zero tumors anywhere. !!!!
Was he taking just Ivermectin or also hydroxy? And do you know at what dosage he was taking? Like how many mg of the IVM per day?
40 mg IVM orally once weekly and Quercetin with bromelain from mercola.
One positive outcome from the covid shitshow is that some have been forced to take control of their own health and question medical dogma. Hidden in plain sight were vitamin D, ivermectin and fenbendazole which we now know help prevent (vitD) and eradicate cancer (IVM, FBZ).
Exactly! There is always a silver lining especially for the ones awake .
What would a protocol look like for managing or eliminating things like inflammation, which is the source for all sorts of bodily havoc? Is it taken daily for the rest of your life? Once a week? Etc?
Most people could benefit from 8000-10,000 IU vitamin D3 per day to help optimize their immune system. A properly functioning immune system, which ‘runs’ on vitamin D, will not attack healthy tissue...which is what autoimmune disease is. Currently the ideal serum level of vitD is 80-100 ng/ml using the 25(OH)D3 blood test, the dose above should get you into that range.
This amount is much higher than the US RDA which is 600 IU per day. This amount is barely enough to keep bones from crumbling! Keeping the population chronically vitD deficient by misinformation and villification of the sun creates customers for life for big pharma treatments to band-aid over the symptoms. Virtually all autoimmune disease can be prevented with adequate vitD and many autoimmune diseases can be cured with vitD. Fun fact: any new ‘miracle’ biologic whose name ends in ‘ib’ or ‘ab’ is an engineered version of vitamin D. For example, all the psoriasis biologics manipulate the interleukins, mostly IL-6 and IL-17. VitD does the same thing...without any side effects like the biologics. Why do the biologics have side effects while vitD doesn’t? Remember the commercial whose tag line was “It’s not nice to fool with Mother Nature...”
Same thing with artemisia annua---chemists had extracted artemisinin, but found, oddly, that it didn't have the same beneficial effect as the whole herb. (PubMed article on medicinal benefit of artemisia). A personal note: suffering from a many-day bad sore throat, I made artemisia annua tea, Monday--found it quite pleasant in an herby-way. Made tea from artem. absinthium yesterday--nasty stuff. Perhaps I used too much.
Where did you find the info that these drugs are forms of vitamin d? I tried a Google search but came up empty.
Strive to live an anti-inflammatory lifestyle. This would include eating a WFPB diet, exercise, being outside in nature (did you know that walking in a forest confers all kinds of health benefits?), intermittent fasting, observing your thoughts and reducing/stopping negative thinking. Consider buying an infrared sauna (Sunlighten is brand we have)... check out Dr. Zach Bush, Dr. Stephanie Sennef. Once you comprehend you are your own doctor, it changes everything for the better. When you are emancipated from western medicine ideology, you will experience true liberation! My best to you! Have no fear!!
would like to know this also.
I take a 12mg Ivermectin tablet once-a-week, along with a 50mg Zinc tablet, along with my other OTC vitamins. I've been doing this as a prophylactic for several months now.
Recently, I've developed some pain and swelling in a pinky finger on my right hand. I had it checked out and X-ray'd by my Ortho Dr. and he indicated that is mildly arthritic.
Question; how often is Ivermectin recommended to be taken? I guessed at once a week as I read somewhere that Ivermectin stays in the body for approximately 6 days?
I have bad arthritis in my spine and deal with a lot of back pain. I took 12 mg of ivermectin for about ten days and saw zero improvement in my back pain. Maybe I needed a higher dose for longer. If anyone has any suggestions, I’d like to hear them.
It could really be that almost everyone has parasites. They are super inflammatory, hard to detect and our medical system will not acknowledge they exist in 1 st world countries. It’s almost as if they don’t want to look for them so you will develop cancer or arthritis. Much more profitable.
100%.... a parasite cleanse including wormwood and anti-parasitics helps many conditions but it needs to be done regularly not just once..... we de-worm our animals but we have stop doing this to ourselves.... we had the wisdom and we were able to take care of ourselves without big pharma or mandates....we have forgotten because they made sure we would forget
It is derived from nature-a fungus in soil from Japan. Firsthand account-a friend of mine 73 yeats old with arthritus knee ad burcitous in elbow, 3 days of Iver all swelling dissapeared and regained all knee movement no pain! Swelling dissapeared.
Could you write more on this, and I will post as article?
Hi! Smartest Guy bar one!
This is a personal enquiry, although I don't know if your credentials allow you to give an 'expert' opinion.
I'm nearly 79, around 155 lbs, fit, active and generally healthy. I can still do 50 press-ups and 200 leg lifts, although periodically these days.
My problem is that because I played local league soccer until 60 every Saturday, Sunday and midweek training during the soccer season, I now have worn joints.
I've had a worsening left hip issue for over 20 years and a right knee problem that causes me to avoid taking too much pressure or weight on that knee. I've been on an NHS hip replacement list for around 15 years but keep saying "it'll do me until next year". So I postpone the op for another year. The Consultant who i visit annually, understands my reasoning that I could be the 1 in 1000 the op goes badly and end up with less mobility than I currently have.
I've been an advocate of IVERMECTIN over the DEATH SHOT since day one (December 2019) and you seem to keep finding many other ailments IVM can assist with. Obviously IVM is primarily an anti-viral medicine, but it seems to be assisting more ailments than seem realistic.
I bought IVM back in 2021 but, apart from sampling one (to see if it killed me) I've not had occasion to test the pills for Covid/Flu or the common cold (possibly all derivatives of each other???).
Our IVM stash came from India so we're not positive it's 'PUKKA' (Boom Boom).
With your latest suggestions it seems IVM might ease rheumatism/arthritis (hip wear) which is what hip replacements are suppose to alleviate.
Have you any knowledge of IVM for worn joint issues?
Cheers!
Mick from Hooe (UK) Unjabbed to live longer!
Mick, I am not a medical doctor, and this Substack does not provide medical advice. You will have to extrapolate and perhaps ask your fellow subscribers their opinions on the matter.
Thank you for your comment.
2nd Smartest,
I do like that 'extrapolate'. It is rewarding to read between your words, just as it was to 'listen between words' two years ago, as John Campbell turned around (but delicately) on the injection issue.
I’m 64 years old and have had juvenile rheumatoid arthritis most likely since I was an infant or toddler. I was “diagnosed” by my pediatrician at age 5 with “arthritis” and then “officially diagnosed” with JRA in ALL joints at age 12. I was also diagnosed at age 37 with Psoriatic Arthritis. So by age 5 I’d lost my ability to cross my legs, sit Indian style, sit on the back of my legs (sorry, not sure how to describe that). Also since then I’ve had a heck of a time getting up and down from the floor and walk like a very old woman (yes, since kindergarten). Also in early elementary school, I lost the ability to make a fist and to bend my wrists in any direction. And of course it’s gotten much worse since then. I’ve had 5 total joint replacements beginning at age 27 and many fusions (surgical and natural) including my lower back. I’ve been told I need surgical intervention on most my remaining joints but I figured they were causing at least as many problems as they solved (I.e., muscle, tendon, and gait issues). I’ve tried many medications but have mainly stuck with hydroxycloriquine and methotrexate.
So that’s a basic overview and I’ve left a lot out but my question is this - would/could ivermectin even help me at this point? I still have lots of inflammation in my joints but I feel it’s mostly due to damage from the JRA (I’m bone on bone in the majority of my remaining joints). It’s nearly impossible to get any of my doctors to test my Vit D levels but the 2 times they did, it was horribly low and high dose Vitamin D was temporarily prescribed. All they really want to do is prescribe biologics but I’ve mostly refused. Also if I start taking Ivermectin, do I immediately stop the other meds? I have so many questions yet no one to ask. Any suggestions for me there?
Any good naturopaths or Functional docs in your area? Check FLCCC website.
Thank you for replying. We do have one functional doc here but they don’t deal with anything resembling my issues. FLCCC shows one functional doc 90 miles away and I just might call them this week. Thank you again.
Might be worth the trip! Good health to you!
IVERMECTIN - Certainly a safer bet than Pfizer's depopulating POISON they pretend is VACCINE!
Could it really be that the disgusting lack of (Vax) quality and efficacy is deliberate? It seems likely.
Not even the most incompetently run organisation could produce 100% useless, dangerous and ineffective crap - unless it was DELIBERATE!
And all this DEADLY garbage being injected with NO LIABILITY for the murdering manufacturers!
Hasn't every man in the street realised what's going on yet? It's nothing to do with the man-enhanced bat virus - but simply about GUARANTEED PROFIT with no regard for the deadly consequences and, of course, population reduction! Courtesy of the WEF's (New World Order).
We know your game and we're coming for you! Be very afraid!
Mick from Hooe (UK) Unjabbed to live longer!
A friend of my mine and my husband has CLL (like me) and his wife has had rheumatoid arthritis since high school (we are all in our 60's). The difference between that guy and me is that he has done ZERO research into what kind of CLL he has, and trusts his oncologist to take care of him (ha, ha) As soon as I know that the IVM and Fenben I'm taking is working for me-which I have no doubt it is-I will get them both to take at least IVM. I've already gotten them on vitamin D, which none of their doctors has ever even mentioned to them, just like the doctor that diagnosed me didn't. When I asked her what I should do for my CLL, her reply was "we'll just watch and wait". Unconscionable!
My friend had a chronic knee problem for most of his life. He lives in Vancouver BC, not a friendly environment for arthritus. He has a second home in Scottsdale Arizonia, where he comes for the desert sun. In may his knee started to cause so much pain he could hardley walk. Went to many chiropractures who used the latest GIZMO technologies ultrasound etc, who said thats all we can do. He ended up a heavy user of Tylonol to mask the pain. He is well aware of the Agenda 2030 and all the evil of kill hot. Being a Canook , he was forced to get jabbed for travel. He knew about properties of Iver for Flu/viral infection (refuse to use word COVID((fear porn)). His elbow started a fluid builup
in elbow (looked like a tennis ball size inflammation., I read about Iver success as anti inflammatory
properties and I suggested he try it, as he had nothing to lose except pain. !2 mcg in morning, 8 ounces of water. wait 1 hour before eating and 3 days later. NO PAIN, 100% knee and elbow normal. He doesnt take Iver, as only when needed. He was truly amazed, as the Phar mafia pain management industry isn't to thrilled about these studies! Being a Canadian he spent about 7 grand for tests etc at the Mayo clinic!
12mcg how much do you think that would be for the paste? I can’t figure it out
I’m 79 and ~ 200 lbs. Recently got something flu like that wouldn’t go away. Took 12 mg ivermectin daily without affecting it. The day after I took 24 mg it almost disappeared. Recommended aggressive dose for me is about 38 mg.
@TMC Thank You for sharing!
Why not just buy this instead of worrying about it?
https://www.virex.health/index.php?route=product/product&product_id=53
Actually wait your right, these are 12 for the dose that’s awesome
I did buy it but it’s sitting in cabinet because they wouldn’t advise for dosage so haven’t used it yet
These links may help you figure out how to measure out what you need. In the you tube video the man shows how to do it. Hope this helps!!
https://youtu.be/AexpeCn08n0?si=jalQbD6IopFdY7Lc
http://www.maximpulse.com/permethrin/ivermectin-calculating-a-dose.html
Thank you Liz for taking the time to help me. Am so grateful.
So kind of you to help Liz and thank you for setting such a good example for other caring people to follow. The info you gave can be very hard to find but is the info that so many seek in desperation. Sadly, very few are willing to answer. We all need to help each other from that place of compassion that lives in our hearts. It is starting to appear that this may be the only real way we have to get out of this nightmare. Thank God for people like yourself🙏 You have inspired me for sure!
Amen and agree! For some reason I have just found the clicks confusing so you helped a lot and my joints thank you in advance
https://www.bitchute.com/channel/mGNBuVjDnfoi/
After pondering all the data on these videos about parasites; it now make more sense as to why CDC, WHO, et al were vehemently against Ivermectin and the seldom mentioned Fenbendazole.
The self protection mechanism of a parasite is clever.
EDTA to rid heavy metals is one more reason to detox.
May God Almighty have mercy on us all.
We are in a fight for our eternity, against all the lies and damn lies...!
Is the Ivermectin taken daily of less often? Is there a standard dose or is it by weight? I've been taking a 12 mg capsule 2X a week, but I haven't noticed much difference in my knee pain. Maybe take more often or a higher dose? Who might have some ideas? Thank you!
Flccc has some good protocols with ivermectin dosing
More possible uses for ivermectin....
Diabetes, Non-Alcoholic Fatty Liver disease, and other Metabolic disorders: "Remarkably, ivermectin displays antidiabetic activities by reducing blood glucose and cholesterol levels, and also by improving insulin sensitivity in an FXR-dependent manner. Our observations therefore indicate that ivermectin may represent a unique safe approach for designing novel FXR ligands for therapeutic purposes."
https://www.nature.com/articles/ncomms2924
https://www.nature.com/articles/srep17288
https://pubmed.ncbi.nlm.nih.gov/23728580/
Asthma:
"We used a mouse asthma model, in which allergic airway inflammation and airway remodelling were induced by ovalbumin (OVA) sensitisation and challenge. Ivermectin or PBS treatment was administered 1 h before OVA challenge. Ivermectin at 2 mg/kg significantly diminished recruitment of immune cells, production of cytokines in the bronchoalveolar lavage fluids and secretion of OVA-specific IgE and IgG1 in the serum. Histological studies indicated that ivermectin suppressed mucus hypersecretion by goblet cells in the airway."
https://link.springer.com/article/10.1007/s00011-011-0307-8
Hypoxia:
Recently, a specific inhibitor of nuclear import has been identified that inhibits importin α/β-dependent import with no effects on a range of other nuclear transport pathways involving members of the importin protein family. In this study we evaluated the physiological activity of this importin α/β-inhibitor (Ivermectin) in the hypoxia response pathway. Treatment with Ivermectin decreases binding activity of HIF-1α to the importin α/β-heterodimer. Moreover, HIF-1α nuclear localisation, nuclear HIF-1α protein levels, HIF-target gene expression, as well as HIF-transcriptional activity are reduced upon Ivermectin treatment. For the first time, we demonstrate the effect of specific importin α/β-inhibition on the hypoxic response on the molecular level.
https://www.degruyter.com/document/doi/10.1515/hsz-2015-0171/html
Anosmia (loss of sense of smell caused by covid):
"There are several theories that explain how anosmia occurs in COVID-19 patients. It is claimed that coronaviruses invade the olfactory pathway through the first order neuron of the central nervous system which presents in the olfactory mucosa. This olfactory mucosa is located in the roof of the nasal cavity and is formed of a specialized neuro-epithelium. The virus reaches the second order neuron by crossing the cribriform plate, and then reaches the olfactory bulb. One potential mechanism for the anosmia brought on by COVID-19 is olfactory epithelium(OE)inflammation. The virus’s attachment to these cells results in cytokine production, which encourages OE inflammation. In one study, IL-6 levels and olfactory abnormalities in COVID-19 patients were compared. Significant relationships between the lowered levels of IL-6 and the length of time needed to recover from anosmia brought on by COVID-19 have been reported. Ivermectin interferes with STAT-3 function and reduces IL-6 production via inhibiting Akt/mTOR signalling and promoting PAK1’s ubiquitin-mediated degradation.The reduction of cytokine production by lipopolysaccharide-exposed macrophages, blocking of NF-kappa B activation and the stress-activated MAP kinases JNK and p38, and inhibition of toll-like receptor 4 (TLR4) signalling were proposed as the mechanism for ivermectin’s anti-inflammatory activity. The results of this study showed a significant reduction in the duration of recovery of patients with persistent post-COVID-19 anosmia. Also, no side effects were reported. In this study patients with persistent post-COVID-19 anosmia treated by local ivermectin in the form of nanosuspension mucoadhesive nasal spray showed statistically significant improvement in the first week of treatment in comparison to the placebo group. The effect of ivermectin nanosuspension mucoadhesive nasal spray in the treatment of post COVID-19 persistent anosmia may be attributed to the direct virucidal effect of ivermectin on persistent viral particles or virions on the nasal mucosa and olfactory bulb, although further molecular research to highlight the mechanism of local ivermectin in recovery of post-COVID-19 anosmia is required."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508858/
Seizures:
"Some antiepileptic and anxiolytic attributes have been reported for IVM in numerous animal models and in clinical trials. A possible pharmacological mechanism of IVM is the contribution of the gamma-aminobutyric acid type-A (GABAA) receptor to its effect and thus it has been suggested that avermectin B1a acts on a modulatory binding site of benzodiazepine receptor and could stimulate it. In other words, IVM acts as a positive allosteric modulator of the GABAA receptor. It has been well established that GABAergic system, and specially GABAA receptors have been considered the main inhibitory neurotransmitter in the central nervous system (CNS), involved in modulating seizure threshold."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647207/
Cytokine Storm:
"IVM may be a good therapeutic tool to inhibit the cytokine storm and prevent ARDS in the following pathways. IVM blocks the IMPα/β1-dependent nuclear import of viral proteins (NS12-RdRp) as mentioned prior. IVM also inhibits the activity of STAT3, subsequently reducing inflammatory IL-6 cytokine production. Besides that, IVM promotes the ubiquitination-mediated degradation of p21 activated kinase 1 (PAK1), a key protein that binds to STAT3 for IL-6 gene transcription, disrupting IL-6 production. The reduction of STAT3 levels by IVM could also bring down HA levels, preventing ARDS in Covid-19 patients. IVM also binds to the viral S protein, thereby prohibiting the attachment of S protein to the host ACE2 receptors for viral entry and reducing the viral load."
Multiple Sclerosis:
"Multiple sclerosis (MS), a T-cell-mediated autoimmune disease that affects the central nervous system (CNS), is characterized by white matter demyelination, axon destruction, and oligodendrocyte degeneration. Here, we conducted in vitro experiments and found that ivermectin inhibited the proliferation of total T cells (CD3+) and their subsets (CD4+ and CD8+ T cells) as well as T cells secreting the pro-inflammatory cytokines IFN-γ and IL-17A; IVM also increased IL-2 production and IL-2Rα (CD25) expression, which was accompanied by an increase in the frequency of CD4+CD25+Foxp3+ regulatory T cells. IVM administration reduced the clinical symptoms of EAE in mice by preventing the infiltration of inflammatory cells into the CNS. Additional mechanisms show IVM promoted Treg cells while inhibiting pro-inflammatory Th1 and Th17 cells and their IFN-γ and IL-17 secretion. IVM also upregulated IL-2 production from MOG35–55-stimulated peripheral lymphocytes. Finally, IVM decreased IFN-γ and IL-17A production and increased IL-2 level, CD25 expression, and STAT5 phosphorylation in the CNS. These results reveal a previously unknown etiopathophysiological mechanism by which IVM attenuates the pathogenesis of EAE, indicating that it may be a promising option for T-cell-mediated autoimmune diseases such as MS. IVM has been shown to stabilize the open state of P2X4 receptor channels, which bind to extracellular adenosine triphosphate and are involved in neurodegenerative disease."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209955/
Rosacea/Atopic Dermatitis:
"Topical IVM improved allergic skin inflammation by reducing the priming and activation of allergen-specific T cells, as well as the production of inflammatory cytokines. While IVM had no major impact on the functions of dendritic cells in vivo and in vitro, IVM impaired T-cell activation, proliferation, and cytokine production following polyclonal and antigen-specific stimulation."
https://onlinelibrary.wiley.com/doi/10.1111/all.13118
https://pubmed.ncbi.nlm.nih.gov/24595578/
IVM Enhances Anticancer Efficacy of Chemotherapeutic Drugs & Reverses Drug Resistance in Cancer Cells Through EGFR/ERK/Akt/NF-κB Pathway:
"Mechanistically, ivermectin reversed the resistance mainly by reducing the expression of P-glycoprotein (P-gp) via inhibiting the epidermal growth factor receptor (EGFR), not by directly inhibiting P-gp activity. Ivermectin bound with the extracellular domain of EGFR, which inhibited the activation of EGFR and its downstream signaling cascade ERK/Akt/NF-κB. The inhibition of the transcriptional factor NF-κB led to the reduced P-gp transcription. These findings demonstrated that IVM significantly enhanced the anti-cancer efficacy of chemotherapeutic drugs to tumor cells, especially in the drug-resistant cells."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580523/
Antiviral:
"We originally identified the small molecule ivermectin as an inhibitor of recognition of HIV-1 integrase (IN) by the importin (IMP) α/β1 heterodimer responsible for IN nuclear import, subsequently establishing ivermectin's ability to inhibit integrase nuclear import and HIV-1 replication. Although other actions of ivermectin have reported, including those targeting DENV NS3 helicase, ivermectin has been clearly shown to inhibit nuclear import of host and viral proteins, including simian virus SV40 large tumour antigen."
https://www.sciencedirect.com/science/article/abs/pii/S0166354219307211
https://www.sciencedirect.com/science/article/pii/S0925443921002271
https://www.frontiersin.org/articles/10.3389/fimmu.2021.663586
Wow!
Thanks Smartest GUY bar one!
In the good old days (Pre-Covid), we could ask our local MD, but things have changed dramatically. The Doctor cannot see humans. He might now be a programmed robot. He forgot his Hippocratic Oath to 'Do No Harm'. He forgot to tell his patients about the many adverse reactions and DEATHS that occur following the useless but deadly Covid injections he refers to as VACCINES! He forgot to tell, his patients that the injection makers bare no responsibility for anything/everything that goes wrong with your health following the injection. He does not confirm Vax recipients are giving 'informed consent'. He's not responded to any of the information I've sent his practice about the proven 'vax' dangers, since the Covid & Vax farce began.
My hip would be a topic he would be reluctant to discuss with me, so I'll have to look elsewhere for health advice. Thanks for your input with your findings to date and if you find any other information relating to IVM and 'arthritis', please let us all know - we understand it's not your medical advice but simply passing on good information.
Cheers!
Mick from Hooe (UK) Unjabbed to live longer!