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aldapooh's avatar

Janssen or J&J is not mRNA based. Spike is there but in J&J it is not supposed to be produced in a body. Correct?

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Cotch's avatar

They both instruct the cells to manufacture the spike. Pfizer and Moderna through mRNA and the others (DNA ones) use adenovirus.

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baboon's avatar

They all do the same thing. mRNA tech (Moderna, Pfizer) uses messenger RNA, the viral vectors (Jansenn, AZ, Sputnik) use adenovirus. They are still "gene therapies". All induce the body to create spoke protein.

Novavax is different as it has nanotechnology for the spikes which are in the injection itself. The Chinese supposedly used a whole inactivated virus.

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OutofStep's avatar

That is the impression I had

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