One of the mechanisms behind the slow kill may be this now recorded shift in antibody cell type from normal IgG(1) ---> IgG4. When your immune system starts forming IgG4 type immunoglobulins, it's essentially tapping out due to overstimulation by a given antigen. Oh, the wonders of turning our cells into mRNA epitope factories over, an…
One of the mechanisms behind the slow kill may be this now recorded shift in antibody cell type from normal IgG(1) ---> IgG4. When your immune system starts forming IgG4 type immunoglobulins, it's essentially tapping out due to overstimulation by a given antigen. Oh, the wonders of turning our cells into mRNA epitope factories over, and over, and over again, discussed in this new paper out of Germany ;
One of the mechanisms behind the slow kill may be this now recorded shift in antibody cell type from normal IgG(1) ---> IgG4. When your immune system starts forming IgG4 type immunoglobulins, it's essentially tapping out due to overstimulation by a given antigen. Oh, the wonders of turning our cells into mRNA epitope factories over, and over, and over again, discussed in this new paper out of Germany ;
https://www.medrxiv.org/content/10.1101/2022.07.05.22277189v1.full.pdf
"Class switch towards non-inflammatory IgG isotypes after repeated SARS-CoV-2
mRNA vaccination"