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Michael Kowalik's avatar

While a handful of vaccine RCTs did use a saline placebo for the control group, these studies did not look at long term health outcomes and had at least one major confounder: the control group was not monitored for other vaccinations, and many vaccines have similar ingredients, adjuvants, contaminants and mechanism of action. A meaningful control group should be previously unvaccinated with any vaccine. Another problem with clinical trials of vaccines is that the tested batch of the vaccine could be of higher purity than subsequent batches, and since most side effects arise due to contamination with non-target antigens/proteins retained from the manufacturing process, poor quality control in some batches could be causing disproportionate amount of autoimmunity and allergies.

A typical vaccine consists of the target antigen/protein and an adjuvant (intended to activate the immune system to the target antigen), plus some non-target antigens - proteins retained as impurities from the manufacturing process. Any injection through the skin stimulates at least two distinct immune responses: IgE (anti-partistic) and IgG (antibodies that fight the target pathogen). IgE sensitisation can be induced by trace amounts of the antigen and typically lasts for life; IgG is relatively short lived and is induced only by higher doses of the antigen. IgE never occurs naturally to many viruses, because it is an anti-parasitic, allergic immune response evolved for insect bites (injections are like insect bites). In the case of natural infection with a respiratory antigen, for example, you typically develop IgG antibodies plus T-cells (which extend the capacity to generate IgG). After receiving a vaccine that includes the same antigen, you get IgE + IgG; that is, allergic sensitisation to the viral protein (and to any other protein in the vaccine) plus some short lived IgG immunity that has to counter both the allergy and the virus itself, at the same time. These two contradictory reactions ensure that vaccines rarely achieve as good immunity as a natural infection, and may also induce allergic sensitivity to any non-target antigens, including the possibility of auto-immunity. Injectable vaccines are inherently dangerous; bad medicine.

This paper includes a reasonably comprehensive bibliography on IgE sensitisation: https://www.longdom.org/open-access/evidence-that-food-proteins-in-vaccines-cause-the-development-of-food-allergies-and-its-implications-for-vaccine-policy-12461.html

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